Category: Nutritional Psychiatry

A Comprehensive Approach to Alleviating Migraines, Anxiety, and Tremors: Integrating Nutritional Psychiatry, a Low-Carb/Carnivore Diet, and Intermittent Fasting


Living with migraines, anxiety, and tremors can be challenging, impacting both physical and mental well-being. Fortunately, emerging research suggests that a comprehensive approach combining nutritional psychiatry, a low-carb/carnivore diet, and intermittent fasting may offer relief from these symptoms. In this blog post, we will explore the principles behind this integrative approach and provide practical tips for incorporating it into your lifestyle.

Understanding the Foundations:

Nutritional Psychiatry:
Nutritional psychiatry focuses on the connection between diet and mental health. Consuming nutrient-dense foods rich in antioxidants, omega-3 fatty acids, and essential vitamins and minerals can help reduce inflammation, support neurotransmitter balance, and enhance overall brain health.

Low-Carb/Carnivore Diet:
A low-carb or carnivore diet emphasizes the reduction or elimination of carbohydrates while prioritizing animal-based proteins and healthy fats. By minimizing carbohydrate intake, this diet aims to stabilize blood sugar levels, reduce inflammation, and optimize brain function.

Intermittent Fasting:
Intermittent fasting involves cycling between periods of eating and fasting. This approach promotes metabolic flexibility and may enhance cellular repair mechanisms, reduce inflammation, and support overall well-being. A common approach is to have an eating window during specific hours of the day and fast for the remaining period.

The Integration Process:

Embrace Whole, Nutrient-Dense Foods:
Incorporate a variety of colorful fruits and vegetables, lean proteins, healthy fats, and nuts/seeds into your diet. Prioritize grass-fed meats, wild-caught fish, leafy greens, and low-carb vegetables to provide essential nutrients for brain health.

Eliminate Seed Oils:
Eliminate seed oils such as soybean, sunflower, safflower, and corn oil from your diet. These oils are high in omega-6 fatty acids, which can promote inflammation. Instead, opt for healthier alternatives like olive oil, coconut oil, lard, ghee, beef tallow, and grass-fed butter.

Mindful Meal Planning:
Work with a healthcare professional or registered dietitian to develop a personalized meal plan. Focus on high-quality animal proteins, healthy fats, and non-starchy vegetables. Experiment with delicious recipes that align with your dietary preferences and restrictions.

Implement Intermittent Fasting:
Start with a 12-hour fasting window overnight and gradually increase to 16 or 18 hours, as tolerated. During the eating window, prioritize nutrient-dense meals to ensure adequate nutrition. Stay hydrated with water and herbal tea throughout the fasting period.

Prioritize Sleep and Stress Management:
Adequate sleep and stress management are vital components of overall well-being. Establish a consistent sleep routine and incorporate stress-reducing techniques like mindfulness, meditation, or yoga into your daily routine.

Regular Exercise:
Engage in regular physical activity to support overall health and well-being. Moderate-intensity exercises like aerobic activities and strength training can improve mood, reduce stress, and enhance brain function.


Taking a comprehensive approach to managing migraines, anxiety, and tremors through nutritional psychiatry, a low-carb/carnivore diet, and intermittent fasting offers a promising strategy for symptom alleviation. However, it’s crucial to remember that individual needs may vary, and it’s essential to consult with a healthcare professional or registered dietitian before making significant dietary changes.

By embracing whole, nutrient-dense foods, eliminating seed oils, and implementing intermittent fasting, you can optimize your brain health and potentially find relief from these debilitating conditions. Prioritize self-care, practice mindful eating, and seek professional guidance to ensure a safe and effective journey towards better health and well-being.

Remember, always consult with your healthcare provider before making any changes to your diet or treatment plan.


Smith R, et al. (2020). The role of nutrition in mental health: Breaking the vicious cycle of poor mental health and unhealthy diets. International Journal of Environmental Research and Public Health, 17(24), 9094. doi: 10.3390/ijerph17249094.
Paoli A, et al. (2019). Beyond weight loss: A review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets. European Journal of Clinical Nutrition, 73(3), 324-333. doi: 10.1038/s41430-018-0341-9.
Patterson RE, et al. (2015). Intermittent fasting and human metabolic health. Journal of the Academy of Nutrition and Dietetics, 115(8), 1203-1212. doi: 10.1016/j.jand.2015.02.018.

Probiotics as Adjunctive Treatment for Depression: A Promising Frontier


Depression is a prevalent and debilitating mental health disorder that affects millions of people worldwide. While current treatment options such as antidepressant medication and psychotherapy can be effective, a significant proportion of individuals with depression do not experience a satisfactory response. This has led researchers to explore novel approaches to treatment, and one such area of investigation is the use of probiotics. Probiotics, which are live microorganisms that confer health benefits when consumed, have shown promise in influencing the microbiota-gut-brain axis and improving depressive symptoms. A recent pilot randomized clinical trial published in JAMA Psychiatry by Nikolova et al. (2023) investigated the acceptability, tolerability, and potential efficacy of probiotics as an adjunctive treatment for depression. The study’s findings shed light on the potential benefits of probiotics and provide a basis for further investigation in larger efficacy trials.

Study Overview

The study conducted by Nikolova et al. included 49 participants with major depressive disorder (MDD) who had an incomplete response to antidepressant medication. The participants were randomly assigned to receive either a multistrain probiotic or a placebo in addition to their ongoing antidepressant treatment. The trial lasted for 8 weeks, during which the researchers assessed various outcomes, including depressive and anxiety symptoms, treatment adherence, tolerability, and adverse reactions.

Key Findings

The results of the study revealed several important findings. Firstly, the probiotic group demonstrated greater improvements in depressive and anxiety symptoms compared to the placebo group. This was evident from the reduction in scores on rating scales such as the Hamilton Depression Rating Scale (HAMD-17), Inventory of Depressive Symptomatology (IDS), Hamilton Anxiety Rating Scale (HAMA), and General Anxiety Disorder (GAD-7). Secondly, the probiotic intervention was well-tolerated, with a high adherence rate and no serious adverse reactions reported. The dropout rate was low, further highlighting the acceptability of probiotics as a treatment option. Finally, the effect sizes observed in the probiotic group were moderate, suggesting a potential therapeutic benefit.

Implications and Future Directions

The findings of this pilot trial provide a solid foundation for further investigation of probiotics as adjunctive treatment for individuals with major depressive disorder. The acceptability, tolerability, and estimated effect sizes on key clinical outcomes indicate that probiotics may offer a promising avenue for improving depressive symptoms. However, it is important to note that this study was a pilot trial with a relatively small sample size, and thus, larger efficacy trials are needed to confirm and build upon these preliminary findings.

The potential mechanisms through which probiotics exert their effects on depressive symptoms are still being explored. The microbiota-gut-brain axis is thought to play a crucial role in influencing mood and behavior, and probiotics may modulate this axis by promoting a healthy gut microbiome. Further research is required to elucidate the specific strains and dosages of probiotics that are most effective in treating depression, as well as to identify the patient subgroups that may benefit the most from this intervention.


Depression is a complex and multifaceted condition that demands innovative treatment approaches. The study by Nikolova et al. contributes to the growing body of evidence supporting the potential use of probiotics as adjunctive treatment for depression. The results demonstrate the acceptability, tolerability, and estimated effect sizes of probiotics in improving depressive and anxiety symptoms. These findings underscore the need for larger, well-designed efficacy trials to confirm the therapeutic potential of probiotics and inform clinical practice. If future studies continue to show promising results, probiotics could represent a safe, accessible, and scalable treatment option for individuals with depression, complementing existing interventions and improving patient outcomes.

Reference Article:

Title: Acceptability, Tolerability, and Estimates of Putative Treatment Effects of Probiotics as Adjunctive Treatment in Patients With Depression: A Randomized Clinical Trial Journal: JAMA Psychiatry Date: June 14, 2023


Author: Stephen Fitzmeyer, M.D.
Physician Informaticist
Founder of Patient Keto
Founder of Warp Core Health
Founder of Jax Code Academy,

Connect with Dr. Stephen Fitzmeyer:
Twitter: @PatientKeto

Exploring the Potential of Ketogenic Diet and Intermittent Fasting in Schizoaffective Disorder Management


Schizoaffective disorder is a complex psychiatric condition characterized by a combination of mood disorders, such as bipolar disorder or major depression, and schizophrenia symptoms. While medication and therapy are commonly used in its treatment, emerging research suggests that dietary interventions, specifically the ketogenic diet and intermittent fasting, may hold promise in managing symptoms and improving overall well-being for individuals with schizoaffective disorder. In this article, we will explore the potential efficacy of adopting a ketogenic diet and intermittent fasting in the management of schizoaffective disorder.

Understanding Schizoaffective Disorder:

Schizoaffective disorder is a challenging mental health condition that often requires a comprehensive approach to treatment. It is characterized by a range of symptoms, including hallucinations, delusions, disorganized thinking, mood disturbances, and cognitive impairments. Conventional treatment typically involves a combination of antipsychotic medications, mood stabilizers, and psychotherapy.

The Potential Benefits of Ketogenic Diet:

  1. Enhanced Mood Stability: The ketogenic diet has been associated with improved mood regulation and stability. By stabilizing blood sugar levels and providing a steady supply of ketones to the brain, the diet may help mitigate mood swings and promote emotional balance, potentially benefiting individuals with schizoaffective disorder.
  2. Cognitive Improvements: Cognitive impairments are common in schizoaffective disorder. The ketogenic diet has shown potential in enhancing cognitive function, including memory and attention. The neuroprotective properties of ketones may help support neuronal health and improve cognitive performance in individuals with schizoaffective disorder.
  3. Reduction in Inflammation: Inflammation has been linked to the development and progression of psychiatric disorders. The ketogenic diet’s anti-inflammatory effects may help mitigate neuroinflammation, potentially contributing to the management of symptoms in schizoaffective disorder.

The Potential Benefits of Intermittent Fasting:

  1. Neuroprotective Effects: Intermittent fasting has been shown to induce cellular stress responses that promote cellular repair and resilience. This process, known as autophagy, may help clear damaged cells and dysfunctional proteins, potentially improving neuronal health and protecting against the progression of schizoaffective disorder.
  2. Regulation of Mood: Intermittent fasting has been associated with improvements in mood and mental well-being. The regulation of neurotransmitters and the production of brain-derived neurotrophic factor (BDNF) during fasting periods may contribute to mood stabilization and alleviate depressive symptoms commonly associated with schizoaffective disorder.
  3. Improved Antipsychotic Medication Efficacy: Some research suggests that intermittent fasting may enhance the effectiveness of antipsychotic medications. Fasting-related changes in metabolic processes and gene expression may influence drug metabolism and efficacy, potentially leading to better symptom management.

Considerations and Consultation:

It is crucial to approach the implementation of a ketogenic diet or intermittent fasting under the guidance of healthcare professionals experienced in these dietary interventions, especially when managing a complex condition like schizoaffective disorder. They can provide individualized recommendations, monitor progress, and ensure nutritional needs are met.

It is important to note that dietary interventions should be integrated into a comprehensive treatment plan that includes regular psychiatric evaluation, medication management, therapy, and other supportive measures tailored to the individual’s needs.


While research on the specific effects of ketogenic diet and intermittent fasting in schizoaffective disorder is limited, emerging evidence suggests their potential benefits in managing symptoms and improving overall well-being. These dietary interventions have shown promise in mood stabilization, cognitive enhancement, reduction of inflammation, and neuroprotection. As with any treatment approach, it is crucial to consult with healthcare professionals to tailor these interventions to individual needs and ensure comprehensive care. Further research is needed to

further investigate the efficacy, safety, and long-term effects of ketogenic diet and intermittent fasting in schizoaffective disorder.

As the field of nutritional psychiatry continues to evolve, exploring the potential of dietary interventions in the management of schizoaffective disorder is an exciting area of research. The ketogenic diet and intermittent fasting offer unique mechanisms that may complement conventional treatment approaches and improve outcomes for individuals with this complex condition.

However, it is important to approach these interventions with caution and under the supervision of healthcare professionals. Each person’s response to dietary changes can vary, and careful monitoring is necessary to ensure that nutritional needs are met, potential side effects are addressed, and the interventions are integrated effectively into the overall treatment plan.

Future studies should focus on conducting rigorous clinical trials to investigate the specific effects of ketogenic diet and intermittent fasting in schizoaffective disorder. This research should explore optimal dietary protocols, long-term sustainability, potential interactions with medications, and the impact on specific symptoms and functional outcomes.

In conclusion, while the ketogenic diet and intermittent fasting show promise in the management of schizoaffective disorder, further research is needed to establish their efficacy, safety, and long-term effects. By combining the advancements in nutritional psychiatry with conventional treatment approaches, we may unlock new possibilities for improving the lives of individuals with schizoaffective disorder and enhancing their mental well-being.

Author: Dr. Stephen Fitzmeyer, M.D.
Physician Informaticist and Founder of Warp Core Health

Connect with Dr. Stephen Fitzmeyer:
Twitter: @PatientKeto

Nutritional Psychiatry: Harnessing the Power of Ketogenic Diet and Intermittent Fasting for Mental Well-being


The field of nutritional psychiatry is gaining recognition as research increasingly highlights the profound connection between diet and mental health. Emerging evidence suggests that dietary interventions, such as the ketogenic diet and intermittent fasting, can play a significant role in the treatment of psychiatric disorders. In this article, we will explore the potential benefits of adopting a ketogenic diet and intermittent fasting as therapeutic strategies for improving mental well-being.

The Ketogenic Diet: Nourishing the Brain

The ketogenic diet is a low-carbohydrate, high-fat eating plan that shifts the body’s metabolism into a state of ketosis. This metabolic state prompts the production of ketones, which become the brain’s primary fuel source, replacing glucose. Here’s how the ketogenic diet can positively impact mental health:

  1. Stabilizing Mood and Mental Clarity: The ketogenic diet has been associated with improved mood stability and mental clarity. By reducing blood sugar fluctuations and providing a steady supply of ketones to the brain, the diet may help regulate neurotransmitters and promote a balanced emotional state.
  2. Reducing Inflammation: Chronic inflammation is often linked to psychiatric disorders. The ketogenic diet has shown anti-inflammatory effects, potentially alleviating inflammation in the brain and contributing to improved mental health outcomes.
  3. Enhancing Neuroprotection: Ketones produced during ketosis have neuroprotective properties, potentially shielding the brain from oxidative stress and supporting neuronal function. This neuroprotective effect may be particularly relevant in the treatment of conditions such as Alzheimer’s disease and epilepsy.

Intermittent Fasting: Resetting the Mind and Body

Intermittent fasting (IF) involves cycling between periods of eating and fasting, which can have profound effects on brain function and mental well-being. Here are some ways IF may benefit mental health:

  1. Promoting Autophagy: During fasting periods, the body enters a state of autophagy, a process where damaged cells and cellular components are recycled and cleared. Autophagy supports cellular renewal and may play a vital role in clearing protein aggregates associated with neurodegenerative disorders.
  2. Enhancing Brain-Derived Neurotrophic Factor (BDNF): IF has been shown to increase the production of BDNF, a protein crucial for the growth and survival of neurons. Higher levels of BDNF have been associated with improved mood, cognitive function, and the prevention of mental disorders.
  3. Regulating Circadian Rhythms: IF helps regulate the body’s internal clock, which governs various physiological processes, including sleep patterns. Proper regulation of circadian rhythms is essential for mental well-being, as disruptions can contribute to mood disorders and cognitive impairments.

Implementing a Nutritional Psychiatry Approach

While the ketogenic diet and intermittent fasting show promise in the treatment of psychiatric disorders, it is essential to approach these interventions with care and under professional guidance. Here are a few considerations:

  1. Personalization: Nutritional psychiatry interventions should be tailored to individual needs and goals. Consulting with a healthcare professional or registered dietitian experienced in these approaches can help determine the most suitable strategies.
  2. Monitoring and Evaluation: Regular monitoring of mental health symptoms and overall well-being is crucial during dietary interventions. Adjustments to the diet or fasting protocols may be necessary to optimize outcomes.
  3. Comprehensive Approach: Nutritional psychiatry should be considered as part of a holistic approach to mental health. It is essential to address other aspects such as exercise, sleep, stress management, and social support to achieve optimal outcomes.


The emerging field of nutritional psychiatry highlights the powerful impact of diet on mental well-being. The ketogenic diet and intermittent fasting offer promising strategies for treating psychiatric disorders by nourishing the brain, reducing inflammation, promoting

Author: Dr. Stephen Fitzmeyer, M.D.
Physician Informaticist and Founder of Warp Core Health

Connect with Dr. Stephen Fitzmeyer:
Twitter: @PatientKeto

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